M5273
 |  |  |
 |
Image
Useful Links & Tools
- MSDS
- Specification Sheet
- Certificate of Analysis
- Certificate of Origin
- M5273 - Product Information Sheet (33 KB)
- Antibiotics biofiles4 (2 MB )
- Antibiotics biofiles4 (2 MB )
- Bulk Quote
M5273
Sigma
Monensin sodium salt
90-95% (TLC)
| Synonym: | Monensin A sodium salt |
| CAS Number: | 22373-78-0 |
| Linear Formula: | C36H61NaO11 |
| Molecular Weight: | 692.85 |
| Beilstein Registry Number: | 4122200 |
| EC Number: | 244-941-7 |
| MDL number: | MFCD00077826 |
| PubChem Substance ID: | 24896992 |
Description
| Biochem/physiol Actions | Na+ ionophore; blocks glycoprotein secretion; may induce catecholamine secretion from chromaffin cells. Useful in potentiometric and spectroscopic studies of alkali metal ion complexes. |
Properties
| assay | 90-95% (TLC) |
| storage temp. | 2-8°C |
Safety
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 36/37/39-45 |
| RIDADR | UN 3462 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | JH2830000 |
References
| reference | Callaway, T.R., et al., Selection of a highly monensin-resistant Prevotella bryantii subpopulation with altered outer membrane characteristics. Appl. Environ. Microbiol. 65, 4753-4759, (1999) Abstract |
| Wang, X.D., et al., Phospholipase C activation by Na+/Ca2+ exchange is essential for monensin-induced Ca2+ influx and arachidonic acid release in FRTL-5 thyroid cells. J. Investig. Med. 47, 388-396, (1999) Abstract | |
| Nebbia, C., et al., Oxidative metabolism of monensin in rat liver microsomes and interactions with tiamulin and other chemotherapeutic agents: evidence for the involvement of cytochrome P-450 3A subfamily. Drug Metab. Dispos. 27, 1039-1044, (1999) Abstract |
